Blar i forfatter "Bogsrud, Martin Prøven"

Viser treff 1-6 av 6

    • Association of low-density lipoprotein cholesterol with risk of aortic valve stenosis in familial hypercholesterolemia 

      Mundal, Liv; Hovland, Anders; Igland, Jannicke; Veierød, Marit Bragelien; Holven, Kirsten Bjørklund; Bogsrud, Martin Prøven; Tell, Grethe S.; Leren, Trond Paul; Retterstøl, Kjetil (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-10-16)
      <i>Importance</i> - Aortic valve stenosis (AS) is the most common valve disease. Elevated levels of low-density lipoprotein (LDL) cholesterol are a risk factor; however, lipid-lowering treatment seems not to prevent progression of AS. The importance of LDL cholesterol in the development of AS thus remains unclear. People with familial hypercholesterolemia (FH) have elevated LDL cholesterol levels ...

    • LDL-cholesterol goal achievement, cardiovascular disease, and attributed risk of Lp(a)in a large cohort of predominantly genetically verified familial hypercholesterolemia 

      Bogsrud, Martin Prøven; Græsdal, Asgeir; Johansen, Dan; Langslet, Gisle; Hovland, Anders; Arnesen, Kjell Erik; Mundal, Liv; Retterstøl, Kjetil; Wium, Cecilie; Holven, Kirsten Bjørklund (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-01-30)
      <i>Background</i> - Current treatment goals for familial hypercholesterolemia (FH) recommended by the European Atherosclerosis Society (EAS) are LDL-C ≤2.5 mmol/L (∼100 mg/dL) or ≤1.8 mmol/L (∼70 mg/dL) in very high-risk subjects.<p> <p><i>Objective</i> - The objective of the present study was to investigate characteristics and treatment status in subjects with genetically verified FH followed ...

    • Loss of statin treatment years during pregnancy and breastfeeding periods in women with familial hypercholesterolemia 

      Klevmoen, Marianne; Bogsrud, Martin Prøven; Retterstøl, Kjetil; Svilaas, Tone; Vesterbekkmo, Elisabeth Kleivhaug; Hovland, Anders; Berge, Christ; van Lennep, Jeanine Roeters; Holven, Kirsten Bjørklund (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-09-03)
      Background and aims Women with heterozygous familial hypercholesterolemia (FH) are recommended to initiate statin treatment at the same age as men (from 8 to 10 years of age). However, statins are contraindicated when pregnancy is planned, during pregnancy and breastfeeding. The aim of the study was to determine the duration of pregnancy-related off-statin periods and breastfeeding in FH ...

    • Postprandial changes in gene expression of cholesterol influx and efflux mediators after intake of SFA compared to n-6 PUFA in subjects with and without familial hypercholesterolemia: secondary outcomes of a randomized controlled trial 

      Øyri, Linn Kristin Lie; Narverud, Ingunn; Bogsrud, Martin Prøven; Hansson, Patrik; Leder, Lena; Byfuglien, Marte Gjeitung; Veierød, Marit Bragelien; Thoresen, Magne; Ulven, Stine Marie; Holven, Kirsten Bjørklund (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-08-13)
      The long-term cholesterol-lowering effect of replacing intake of SFA with PUFA is well established, but has not been fully explained mechanistically. We examined the postprandial response of meals with different fat quality on expression of lipid genes in peripheral blood mononuclear cells (PBMC) in subjects with and without familial hypercholesterolaemia (FH). Thirteen subjects with FH (who had ...

    • Profiling of immune-related gene expression in children with familial hypercholesterolaemia 

      Narverud, Ingunn; Christensen, Jacob J.; Bakke, Siril Skaret; Ulven, Stine Marie; Rundblad, Amanda; Aukrust, Pål; Espevik, Terje; Bogsrud, Martin Prøven; Retterstøl, Kjetil; Ueland, Thor; Halvorsen, Bente; Holven, Kirsten Bjørklund (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-10-21)
      <i>Background</i> - Innate and adaptive immune responses are pivotal in atherosclerosis, but their association with early‐stage atherosclerosis in humans is incompletely understood. In this regard, untreated children with familial hypercholesterolaemia may serve as a human model to investigate the effect of elevated low‐density lipoprotein (LDL)‐cholesterol.<p><p> <i>Objectives</i> - We aimed ...

    • Risk of Ischemic Stroke and Total Cerebrovascular Disease in Familial Hypercholesterolemia 

      Hovland, Anders; Mundal, Liv; Igland, Jannicke; Veierød, Marit Bragelien; Holven, Kirsten Bjørklund; Bogsrud, Martin Prøven; Tell, Grethe S.; Leren, Trond Paul; Retterstøl, Kjetil (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-11-21)
      <p><i>Background and Purpose</i>: Familial hypercholesterolemia (FH) is a common autosomal dominant disease leading to increased level of serum LDL (low-density lipoprotein) cholesterol and risk of coronary heart disease. Whether FH increases the risk of cerebrovascular disease, including ischemic stroke, is debated. Accordingly, we studied the incidence of cerebrovascular disease in a cohort of ...